WebDec 31, 2024 · Human cytomegalovirus (HCMV) encodes four homologs of G protein coupled receptors (vGPCRs), of which two, designated UL33 and US28, signal constitutively. UL33 and US28 are also conserved with chemokine receptors: US28 binds numerous chemokine classes, including the membrane bound chemokine, fractalkine; … WebJul 16, 2015 · Protein interactions form a network whose structure drives cellular function and whose organization informs biological inquiry. Using high-throughput affinity …
(PDF) BioPlexR and BioPlexPy: integrated data products
WebDescription The BioPlex package implements access to the BioPlex protein-protein interaction networks and related resources from within R. Besides protein-protein interaction networks for HEK293 and HCT116 cells, this includes access to CORUM protein complex data, and transcriptome and proteome data for the two cell lines. WebDescription The BioPlex package implements access to the BioPlex protein-protein interaction networks and related resources from within R. Besides protein-protein … how many lifesavers are in a 50 oz bag
Import and representation of BioPlex PPI data and related resources
WebApr 12, 2024 · Background: Organophosphate esters (OPEs) are common endocrine-disrupting chemicals, and OPE exposure may be associated with type 2 diabetes (T2D). However, greater knowledge regarding the biomolecular intermediators underlying the impact of OPEs on T2D in humans are needed to understand biological etiology. … WebPalmitoyl-protein thioesterase 1 (PPT1) is a depalmitoylation enzyme that is mutated in cases of neuronal ceroid lipofuscinosis (NCL). The hallmarks of the disease include progressive neurodegeneration and blindness, as well as seizures. In the current study, we identified 62 high-confident PPT1-binding proteins. These proteins included a self … WebMay 5, 2024 · A series of validation experiments examining: 1) interactions of 12 poorly studied BioPlex 2.0 proteins in HCT116 cells (Extended Data Fig. 1b–m), 2) reciprocal … how many lifesavers in a roll