WebAug 9, 2024 · Alpha-2 agonists can cause bradycardia and hypotension. tolerance and withdrawal to alpha-2 agonists. Perhaps the greatest drawback of alpha-2 agonists is the possibility of developing tolerance and withdrawal. Over time, patients may become tolerant to the medication, causing reduced clinical efficacy. WebVomiting and diarrhea that lead to dehydration, high blood sodium levels (hypernatremia), and heart failure. Bleeding or leaking amniotic fluid in pregnant women. Higher risk of overdosing on an ...
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WebAug 16, 2009 · Now opiates / opioids, basically the opposites of stimulants- "uppers" are CNS depressants, so they actually lower blood pressure, lowers heart rate, slows down your breathing rate to where its regulated at a very slow and light pace, it also causes respiratory depression causing more the larger the dose that is taken, and slows and relaxes ... WebMost opioids have little direct negative effect on cardiac contractility. However, opioid administration can be associated with decreased cardiac function when administered in … china population 2012
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